B1 under 1:8
B2 under 1:8
B4 under 1:8
B5 under 1:8
reference: under 1:8
B1 under 1:10
B4 over 1:640
B6 under 1:10
reference: under 1:20
In two results from the same blood draw of October 2009, my daughter got these discrepant results.
October 2009, at Focus Diagnostics
b2 under 1:8
October 2009, at ARUP labs
b1 under 1:10
b4 over 1:640
b6 under 1:10
"Micro-neutralization test - Persistently elevated antibody levels for one or more enteroviruses over years can suggest a chronic enteroviral infection. The Micro-neutralization test is a very sensitive, specific test and only 11 enteroviruses, coxsackie B 1-6 and echoviruses 6,7,9,11 and 30 can be tested by using this method. Titers of 1:320 and higher are good indications of current infection.
In 2007, Dr. John Chia and his son Andrew Chia, found 82% of 165 patients postiive in stomach biopsies for VP1 - enteroviral capsid protein. VP1 testing for enteroviruses was done from blood from ME patients as far back as the late 1980's by Professor James Mowbray and Dr. John Richardson in the UK (until this VP1 test was "deeped sixed" by Wessely in 1989.)
To some this might look like an insignificant detail. Quite the contrary: a clear viral association (not necessarily cause) with ME/CFS would be a tremendously big deal - and potentially nail down one corner of this illness.
It is time to reignite interest in the association of enteroviruses in ME/CFS. Confirming this would be a big step in the right direction - and perhaps encourage drug companies to wake up regarding enteroviral drug research. Nailing down an enteroviral associaton with ME/CFS would not take years of research. It could be done quickly. Dr. Chia has given us the start. Hepatitis drugs are coming down the pipeline - and they might work. Researchers, clinicians and patients need to do more to raise awareness of establishing enteroviral association with ME/CFS.
As patients we can help by switching out these tests and seeing what results are gotten.
Several more articles on enteroviruses can be found at InvestinME here and here.